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2025 Poster Session A

A74 - Characterizing the Persistent Impacts of Chronic and Acute Early Life Stress on Fear and Anxiety-Related Behaviors in Adult Male and Female Rats

This experiment addresses how chronic early life stress later affects fear responses and anxiety-like behavior in adulthood.

2025 Poster Session A

A74 - Characterizing the Persistent Impacts of Chronic and Acute Early Life Stress on Fear and Anxiety-Related Behaviors in Adult Male and Female Rats

Mentor: Jennifer J. Quinn, Ph.D.

This experiment addresses how chronic early life stress later affects fear responses and anxiety-like behavior in adulthood. Animals who received cELS and no adult fear conditioning were predicted to exhibit an anxiety-like phenotype, measured as increased time spent by perimeter walls (thigmotaxis), in the open field test. The addition of adult fear conditioning was predicted to heighten the anxiety-like phenotype. It was found that animals who received cELS did not exhibit SEFL in adulthood. Additionally, distance traveled appears to be a more sensitive measure for anxiety-like behavior as opposed to thigmotaxis.